Forty-nine students who registered for fall classes at the University of Virginia have been disenrolled after failing to meet the school’s vaccine mandate, officials said Friday.

The campus unveiled its vaccine mandate in May and the overwhelming majority of the campus is in compliance, officials said. More than 96 percent of U-Va. students are vaccinated against the coronavirus and 335 students with religious and medical exemptions have been granted permanent waivers, officials said…

Vaccines remain a key piece of the university’s reopening strategy, Jim Ryan, the university’s president, said at a town hall this month.

“We are in a much better and much different position than we were last year, primarily because of the vaccines and the extraordinarily high vaccination rate in our community,” Ryan said. “This means we can return in person to classes, activities, sporting events and research labs as we have been planning to do in the fall semester, with the residential experiences that are at the heart of this university.”