The Food and Drug Administration on Thursday announced it will order top-seller Juul to take its e-cigarettes off the shelves in the U.S. market.

Why it matters: The move comes amid a push to cap nicotine in cigarettes and signals the Biden administration is escalating its attempt to limit tobacco use in the U.S., Axios’ Arielle Dreher reports.

The big picture: The decision follows a nearly two-year review by the FDA of Juul’s data as the vaping company sought authorization for its products to stay on the U.S. market, according to the Wall Street Journal.

What they’re saying: “Today’s action is further progress on the FDA’s commitment to ensuring that all e-cigarette and electronic nicotine delivery system products currently being marketed to consumers meet our public health standards,” FDA commissioner Robert M. Califf said in a statement.