Terry Orie, a 61-year-old real estate agent, has skipped vacations because of the pandemic. She has canceled plans with friends. She has bristled at the frustrations of communicating with clients when everybody is wearing masks.

Ms. Orie is fed up with the coronavirus’s effects on her life. And she knows exactly whom to blame. “I don’t get it, I don’t get why they don’t wear masks and why they won’t get vaccinated,” she said Friday, sitting outside a Whole Foods in Fairfax with her 14-year-old toy poodle, Tootsie. “People think it’s their God-given right to put everybody else’s health at risk.”…

Polling from across the country shows that broad numbers of Americans support tightening vaccine requirements for schools, hospitals and workplaces. Majorities favor showing proof of vaccination to travel by airplane, attend a concert, eat at a restaurant or stay in a hotel. And most vaccinated voters blame the unvaccinated — not the administration — for the skyrocketing resurgence of the virus.

“People are frustrated,” Mr. McAuliffe said in an interview. “They’re frustrated because people won’t get vaccinated. I’m running against a guy who has told college students: ‘You don’t want to get it? Don’t get it.’”