Charlie Gard’s parents have been given 48 hours to produce new evidence illustrating how experimental treatment could improve the condition of their critically ill 11-month-old son.

At an emotional high court hearing on Monday, punctuated by angry interventions by Charlie’s parents, Mr Justice Francis said he would be “delighted” to be able to change his mind from his decision in April not to allow the baby to be flown to the US but it would take “drastic” new evidence for him to do so.

Sitting at the high court, he said that by 2pm on Wednesday Connie Yates and Chris Gard must produce the evidence they claim to have, including “when it was published, when it became available to them”. There will then be a hearing on Thursday which could decide Charlie’s fate.