According to a new study released by the Centers for Disease Control Thursday, the number of monthly calls to poison centers for e-cigarette related incidents went from one per month in September 2010 to 215 per month in February 2014.

The jump takes the proportion of e-cigarette related calls to poison centers from just 0.3 percent to 41.7 percent.

Published in the Morbidity and Mortality Weekly Report, the study sheds light on the hidden dangers of what many consider to be a promising alternative to regular cigarettes. The culprit of the rising calls, according to the CDC, is directly related to e-cigarette’s colorful and enticing packaging. Incidents involving children below the age of 5 make up 51.1 percent of the poison center calls.