Hizzoner went on to defend the city’s healthcare workers and told Cuomo to lay off the threats.

“Does he think that our healthcare professionals are uninterested in vaccinating people? How about trusting the people who have been our heroes?” de Blasio said.

“Help them, support them, don’t fine them, don’t threaten them, respect them and help them.”

Cuomo earlier Monday deflected blame on the state’s sluggish inoculation effort — which has seen large quantities of the vaccine supply unused — to local leaders, including de Blasio.