March: States are charged with distributing still-limited supplies of the vaccines and determining which adults get high priority. Those over the age of 65 are expected to be at the top of the list. More data about the safety and efficacy of vaccines should be available from people who got the vaccine in December and January, including whether either vaccine causes major side effects in adults, Slifka said.

— Signs of normalcy: March Madness, the college basketball tournament that was canceled in 2020, will get under way in a bubble in Indianapolis. But most of us will be watching Eddie Murphy in Coming 2 America at home rather than venturing out to theaters.

April: By now two additional vaccine candidates, from AstraZeneca and Johnson & Johnson, could get emergency use authorization from the FDA. Public health experts also expect to see additional therapies get EUA from the FDA, further reducing Covid deaths.

— Signs of normalcy: Major League Baseball has scheduled opening day for April 1, and the season could go smoothly if the vaccine proves to be effective, Hotez said.