“I oppose the nomination of Judy Shelton because I am not convinced that she supports the independence of the Federal Reserve Board as much as I believe the Board of Governors should,” Alexander said in a statement to the Washington Post. “I don’t want to turn over management of the money supply to a Congress and a President who can’t balance the federal budget.”

Democrats are also expected to oppose Shelton’s nomination, and Republicans hold a 53-47 majority in the Senate. It is unclear whether Vice President Pence, who is marshaled in to break ties in the Senate, will have to do so; a spokesman for Alexander said he will not be in Washington this week due to family matters, so he won’t be present to vote on the nomination if it occurs this week.

But Sen. Rick Scott (R-Fla.), who is expected to support Shelton, will be in quarantine this week, according to spokesman Chris Hartline, after coming into contact with someone Friday night in Naples, Fla., who later tested positive.