“It’s difficult when you think you have a light at the other end of the tunnel to look forward to, and then all of a sudden you realize it’s a train,” said Rice, 44, a program coordinator at Arizona State University.

An exhausted, exasperated nation is suffering from the effects of a pandemic that has upended society on a scale and duration without parallel in living memory.

The Rice family and millions of other Americans are wrestling with difficult questions about how to juggle school, pay their bills and look after their mental and physical health.

Parents lie awake, their minds racing with thoughts of how to balance work with their newfound role as home-schoolers. Frontline health workers are bone tired, their nerves frayed by endless shifts and constant encounters with the virus and its victims. Senior citizens have grown weary of isolation. Unemployed workers fret over jobs lost, benefits that are running out, rent payments that are overdue. Minority communities continue to shoulder the disproportionate burden of the contagion’s impact, which in recent weeks has killed an average of about 1,000 people a day.