Our Kanye sources tell us, he suffers a serious bout with his bipolar disorder, usually once a year … and our sources say Kanye’s in the midst of one now.

As you know, Ye announced he’s running for president via Twitter over the weekend, and also did a rambling interview with Forbes … which drew harsh criticism, confusion and concern.

Our sources say his family and those close to him are worried, but they believe things will stabilize as they have in the past. The problem here, we’re told — Kanye’s proclamations are causing problems.