The longtime cable host, 49, had a mini-existential crisis on his SiriusXM show, lashing out at his lucrative primetime gig and blasting President Trump as being “full of s–t.”

“I don’t want to spend my time doing things that I don’t think are valuable enough to me personally,” Cuomo said. “I don’t value indulging irrationality, hyper-partisanship.”

Cuomo said his battle with COVID-19 has made him rethink his values and question his position as a public figure.

“I don’t like what I do professionally,” he said. “I don’t think it’s worth my time.”