Sens. Bill Cassidy of Louisiana and Lindsey Graham of South Carolina and their allies on Capitol Hill and in the White House continued to work on tweaking their plan on Friday evening even after Sen. John McCain of Arizona dealt the bill an apparent death blow on Friday afternoon. A new version of the legislation could drop as soon as this weekend, those sources said.

McCain and Sen. Rand Paul of Kentucky oppose the bill to block grant the federal health care program to the states, and Sen. Susan Collins of Maine is leaning against voting for the bill. The changes may be aimed at Sen. Lisa Murkowski of Alaska, whose sparsely populated state suffers from unique health care costs and challenges.

As of Friday evening, Murkowski was uncommitted. Her spokeswoman said that “Nothing has changed.”