McCain, who had voted for a motion to proceed to the bill Tuesday after returning to Washington following surgery for a brain tumor, held out all day, including in a news conference where he criticized the partisan process that led to the after-midnight vote.
His surprise decision came after a prolonged drama on the Senate floor. Multiple Republican colleagues, including Vice President Mike Pence, engaged in animated conversations with the Arizona senator who has long cherished his reputation as a maverick.
At one point before the final vote, Trump called Pence, who handed the phone to McCain, a source briefed on the call told CNN. The call, just off the Senate floor, was brief and ultimately unsuccessful.