In a country as diverse as ours, Thanksgiving can mean a lot or very little. Some people don’t live near their family, or don’t get along with their family, and prefer to work on that day.
Others value other holidays over Thanksgiving. Some people came to America from Russia as a child with a family that proceeded to celebrate Thanksgiving (on Friday!) with vodka and caviar, same as any other holiday, no turkey in sight.
Nobody polls these people to find their opinions before organizing petitions to push stores to close.
There’s also a whiff of hypocrisy to all of it. The anti-shopping protests inevitably target big-box retailers. Few mind that supermarkets are open on Thanksgiving.