Mayhem erupted outside Columbia University’s graduation Wednesday as some students burned their diplomas and cops tussled with dozens of rowdy anti-Israel demonstrators, arresting at least two people.

Fired-up anti-Israel students on campus for the Upper Manhattan ceremony also tried to drown out acting President Claire Shipman’s commencement address — with raucous chants of “free Palestine!” and demands for the release of former Columbia grad student Mahmoud Khalil, who was detained by ICE agents in March and is currently awaiting deportation.

“The prisoners have taken control over the asylum,” said Liora Rez, founder of advocacy group StopAntisemitism, to The Post.

Outside the commencement ceremony, which involved about 12,000 graduates and an estimated 25,,000 family and friends, some newly minted anti-Israel grads torched their diplomas, loudly booing, chanting and brandishing signs denouncing the Jewish state for alleged “atrocities” committed in its war against Hamas.