The contributions to Ryan from AmerisourceBergen, McKesson and Dublin, Ohio-based Cardinal Health, the three biggest drug distribution companies in the U.S., rolled in between 2007 and August of this year.

Earlier this year, the companies finalized a $21 billion settlement with state, local and Native American tribal governments and others over the toll of the opioid crisis. The settlement is the largest over opioid claims and keeps the companies from facing thousands of lawsuits.

The trio’s combined giving to Ryan of $27,000 represents a fraction of the campaign contributions he has collected over the years, which include $8.6 million for the Senate race as of July. Still, they are notable as Ryan hammers the spotty record of the anti-opioid nonprofit started by his Republican opponent, “Hillbilly Elegy” author JD Vance.