In closely divided states and congressional districts around the country, many moderate voters suddenly find themselves choosing between a Democratic Party that has disappointed them since taking power in 2021, and a Republican Party newly emboldened to enact a right-wing social agenda that makes many voters deeply uneasy.

That could create a major challenge for Republicans in their efforts to win back the centrist and center-right communities that shunned them during the Trump years and turned America’s suburbs — from areas near Atlanta and Philadelphia to Minneapolis and Salt Lake City — into at least a temporary political desert for the party. That exodus was particularly pronounced among centrist and even Republican-leaning white women, a constituency that tends to favor abortion rights with modest limitations…

Plenty of voters feel more conflicted. Nancy Turtenwald, 64, of West Allis, Wis., an inner-ring suburb of Milwaukee, said she had voted Republican her entire life but also supported abortion rights. Ms. Turtenwald said she would prefer that abortion not be the main issue in the country’s political discourse, citing access to health care, the cost of gas and housing, and the availability of baby formula as more important issues.

If Roe is overturned and Republicans attempt to ban abortion, Ms. Turtenwald said, she will consider crossing over to vote for Democrats. “I think a lot of women would,” she said.