The big picture: A wave of Democratic retirements has given progressives multiple openings to target seats for a shift left.

In New York, moderate Rep. Tom Suozzi (D-N.Y.) is running for governor and progressive state Sen. Alessandra Biaggi has announced a bid to succeed him.

In Pennsylvania, progressives including state Rep. Summer Lee are running to replace retiring Rep. Mike Doyle (D-Pa.).

Progressives also are eyeing seats in North Carolina, California, Illinois, Maryland and Florida being vacated by non-CPC members, and plan to make more endorsements throughout the cycle, Axios is told.