“There is a process on amendments, and you can be assured that we’ll have a robust amendment process during the vote-a-rama,” Senate Minority Leader Mitch McConnell (R-Ky.) told reporters during a recent press conference.

Republicans took a similar tack on a coronavirus relief bill earlier this year, where concerns that they could peel off Sen. Joe Manchin (D-W.Va.) on an unemployment amendment threw the bill into limbo for hours as Democrats tried to cut a deal with Manchin.

Republicans could try to peel off Manchin — who has pushed back on paid leave language, a nicotine tax and climate provisions — and Sen. Kyrsten Sinema (D-Ariz.) as well as Democrats up for election next year.

“The best thing we can do if we want to change the bill, or derail it … you’ve got to figure out a way you can make amendments attractive to Dems,” Thune said.