Vaccines are great. Masks make them even better.

But even vaccinated immune systems can be somewhat foiled when local conditions change. A well-armored bank will still be better off than an unsecured one, but could struggle to thwart career criminals—ones who are savvy enough to show up en masse, move fast, and use brutal tactics. And more of those robbers might make it out of the scuffle unscathed and eager to hit up a neighboring bank. Vaccine-prepped immune systems are still mostly clobbering Delta, the SARS-CoV-2 variant that’s now found in 80 percent of the virus samples being sequenced across the nation: People who have gotten all their shots are a lot less likely to experience symptoms, hospitalization, or death, and don’t seem to be responsible for much virus transmission. But Delta also appears to be especially good at accumulating in airways, and seems to eke past some of our immune defenses. These troubling traits might make it easier for the virus to mildly sicken some inoculated individuals, and perhaps spread from them as well. Vaccines are an imperfect shield; variants like Delta find their way through the cracks.

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Masks cut down on all of this risk. If vaccines shore up security from the inside, face coverings (which, you know, literally cover your face) erect a sturdy blockade around the bank’s exterior—fences, bars, better locks, and ID checks at an intruder’s typical point of entry. Masks are physical barriers; they’re “great at preventing exposure to large doses of virus” before the invaders even enter the premises, Iwasaki said. And in the same way that it’s easier for security guards to incapacitate just a few crooks busting through the door, “the less virus you need to fight off, the better—I think that’s pretty clear,” Marion Pepper, an immunologist at the University of Washington, told me. Masks, in other words, curb the amount of labor our immune systems are forced to do—in some cases, maybe eliminating the threat entirely. In that way, they accomplish something vaccines can’t: Unlike immune cells, they don’t have to wait until after the virus has broken into the body to act. That’s an especially big asset for people whose bodies are less equipped to respond to vaccines, including the elderly and the immunocompromised, populations the CDC says should mask more vigilantly indoors, regardless of where they live.

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