A week before the CDC mask announcement, a major study showed that almost half of people living with organ transplants produce zero antibodies after two doses of vaccine, including nearly 60% of people on the drugs that Anmol takes. The very drugs keeping his body from rejecting his kidney make him vulnerable to infection from SARS-CoV-2 and other pathogens. There are a lot of Americans like my brother. There have been more than 850,000 organ transplants in the U.S. since 1988, including 39,000 during 2020. An estimated 2.7% of all Americans are immunocompromised, many of them because they are taking the same drugs as transplant recipients for Crohn’s disease, psoriasis, and other autoimmune diseases. President Biden said, “If you’re fully vaccinated and can take your mask off, you’ve earned the right to do something that Americans are known for all around the world: greeting others with a smile.” Anmol is vaccinated, and always greets people with a smile. But he can’t show it in public. Not yet.