A third of Americans are showing signs of clinical anxiety or depression, Census Bureau data shows, the most definitive and alarming sign yet of the psychological toll exacted by the coronavirus pandemic.

When asked questions normally used to screen patients for mental health problems, 24% showed clinically significant symptoms of major depressive disorder and 30% showed symptoms of generalized anxiety disorder.

The findings suggest a huge jump from before the pandemic. For example, on one question about depressed mood, the percentage reporting such symptoms was double that found in a 2014 national survey.

The troubling statistics were released last week in a tranche of data from the Census Bureau. The agency launched an emergency weekly survey of U.S. households at the end of April to measure the pandemic’s effects on employment, housing, finances, education and health. In the most recent data release, 1 million households were contacted between May 7 and 12, and more than 42,000 responded.