A decades-old malaria medicine touted by the president as a coronavirus treatment showed no benefit for thousands of patients hospitalized in New York.

There was also no noticeable advantage for patients that took the drug paired with the antibiotic azithromycin, according to hotly anticipated research published Monday in the Journal of the American Medical Association.

President Donald Trump had repeatedly championed hydroxychloroquine from the press briefing stage, saying it had “tremendous promise” and was safe because “it’s been used for a long time.”

Previous trials had suggested the drug can cause serious heart problems, especially when paired with azithromycin, and the latest study backed up those findings. Researchers said that patients receiving both drugs together were more likely to experience cardiac arrest than those who received one or neither of the therapies.