Study: Two-thirds of coronavirus patients improve after taking remdesivir

The paper’s author called the findings “hopeful,” but cautioned that it is difficult to interpret the results since they do not include comparison to a control group, as would be the case in a randomized clinical trial. In addition, the patient numbers were small, the details being disclosed are limited, and the follow-up time was relatively short…

Before the treatment, 30 patients were on mechanical ventilators, and four were on a machine that pumps blood from the patient’s body through an artificial oxygenator. After a median follow-up of 18 days, 36 patients, or 68%, had an improvement in oxygen-support class, including more than half of the 30 patients receiving mechanical ventilation who had their breathing tubes removed. A total of 25 patients, or 47%, were discharged from the hospital. Seven patients, 13% of the total, died.

Twelve patients, 23%, had serious side effects including multiple-organ-dysfunction syndrome, septic shock and acute kidney injury.