Researchers at the South China Agricultural University in Guangzhou suggested pangolins as the animal source at a press conference on 7 February. Pangolins are highly sought-after in China for their meat and their scales; the latter are used in traditional medicine. Although sales of the animal are forbidden in China as part of a worldwide ban, they are still smuggled in from a handful of southeast Asian and African countries. The researchers said they had found a coronavirus in smuggled pangolins that was a 99% genetic match to the virus circulating in people.
But the result did not actually refer to the entire genome. In fact, it related to a specific site known as the receptor-binding domain (RBD), say the study’s authors, who posted their analysis1 on the biomedical preprint server bioRxiv on 20 February. The press-conference report was the result of an “embarrassing miscommunication between the bioinformatics group and the lab group of the study”, explains Xiao Lihua, a parasitologist at the South China Agricultural University and a co-author of the paper. A whole-genome comparison found that the pangolin and human viruses share 90.3% of their DNA.