When a researcher gets proved wrong, that means the scientific method is working. Scientists make progress by re-doing each other’s experiments—replicating them to see if they can get the same result. More often than not, they can’t. “Failure to reproduce is a good thing,” says Ivan Oransky, co-founder of Retraction Watch. “It happens a lot more than we know about.” That could be because the research was outright fraudulent, like Wakefield’s. But there are plenty of other ways to get a bum result—as the Public Libary of Science’s new collection of negative results, launched this week, will highlight in excruciating detail.
You might have a particularly loosey-goosey postdoc doing your pipetting. You might have picked a weird patient population that shows a one-time spike in drug efficacy. Or you might have just gotten a weird statistical fluke. No matter how an experiment got screwed up, “negative results can be extremely exciting and useful—sometimes even more useful than positive results,” says John Ioannidis, a biologist at Stanford who published a now-famous paper suggesting that most scientific studies are wrong.
The problem with science isn’t that scientists can be wrong: It’s that when they’re proven wrong, it’s way too hard for people to find out.
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