He said: ‘Religion is more difficult to talk about. I don’t think we could do Life of Brian any more. A parody of Islam would be even harder.
‘We all saw what happened to Salman Rushdie and none of us want to get into all that. It’s a pity but that’s the way it is. There are people out there without a sense of humour and they’re heavily armed.’
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In 1989, Mr Rushdie was forced into hiding after the Supreme Leader of Iran, Ayatollah Ruhollah Khomeini, issued a fatwa calling for him to be killed in revenge for his novel The Satanic Verses.
Ahead of a series of live reunion shows in July, Mr Palin admitted much of his Monty Python material would now seem dated to modern audiences.
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