Study: Father’s diet may affect offspring’s development

These epigenetic markers don’t change the genetic information, but rather switch parts of the genome on and off. They are susceptible to environment and diet throughout fetal development, but were thought to be wiped clean before birth. New studies, including the one published online Tuesday in Nature Communications, have revealed that some of them may survive all the way from sperm to baby.

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When analyzing the sperm epigenomes of the low-nutrition mice, the researchers found abnormalities in epigenetic markers that affected genes linked to development, neurological and psychological disorders and certain cancers.

“We should be looking carefully at the way a man is living his life,” said study author and reproductive biologist Sarah Kimmins of McGill University. “Environmental exposure is remembered in the developing sperm and transmitted to offspring.”

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