New York Mayor Michael Bloomberg blasted Wall Street protesters, entering their 22nd day Saturday, for targeting the financial sector and “trying to destroy the jobs of working people in the city.”

Speaking on WOR radio Friday, Bloomberg said the city’s labor unions — many of whom swelled demonstrator ranks earlier this week — depend on salaries that “come from the taxes paid by the people they’re trying to vilify.”

Still, the mayor described the city’s unemployment rate as “unacceptably high,” and acknowledged that “a lot of people are disaffected.”

“Some are legit, some aren’t,” Bloomberg said, describing the concerns of the demonstrators in Lower Manhattan.