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A waitress, Pheobe Best, said that the site had provoked fights and caused divorces. The diner’s owner, Jim Deverell, called Topix a “cesspool of character assassination.” And hearing the conversation, Shane James, the cook, wandered out of the kitchen tense with anger.

His wife, Jennifer, had been the target in a post titled “freak,” he said, which described the mother of two as, among other things, “a methed-out, doped-out whore with AIDS.” Not a word was true, Mr. and Ms. James said, but the consequences were real enough.

Friends and relatives stopped speaking to them. Trips to the grocery store brought a crushing barrage of knowing glances. She wept constantly and even considered suicide. Now, the couple has resolved to move.

“I’ll never come back to this town again,” Ms. James said in an interview at the diner. “I just want to get the hell away from here.”