Pakistan’s detention of five C.I.A. informants, including a Pakistani Army major who officials said copied the license plates of cars visiting Bin Laden’s compound in Abbottabad, Pakistan, in the weeks before the raid, is the latest evidence of the fractured relationship between the United States and Pakistan. It comes at a time when the Obama administration is seeking Pakistan’s support in brokering an endgame in the war in neighboring Afghanistan.

At a closed briefing last week, members of the Senate Intelligence Committee asked Michael J. Morell, the deputy C.I.A. director, to rate Pakistan’s cooperation with the United States on counterterrorism operations, on a scale of 1 to 10.

“Three,” Mr. Morell replied, according to officials familiar with the exchange…

It is the future of the drone program that is a particular worry for the C.I.A. American officials said that during his meetings in Pakistan last week, Mr. Panetta was particularly forceful about trying to get Pakistani officials to allow armed drones to fly over even wider areas in the northwest tribal regions. But the C.I.A. is already preparing for the worst: relocating some of the drones from Pakistan to a base in Afghanistan, where they can take off and fly east across the mountains and into the tribal areas, where terrorist groups find safe haven.