Pelosi to donors: These will be the toughest midterms we've ever faced

Pelosi’s comments acknowledge a stark reality for Democrats. The president’s party almost always loses seats in a midterm election, especially in a president’s first term. But Democrats’ ambitious agenda–healthcare reform, climate legislation, etc.–combined with a still-lackluster economy makes Pelosi’s party particularly vulnerable in 2010.

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Many analysts have drawn parallels to 1994, when Democrats’ suffered heavy losses in the midterms after an ambitious attempt to overhaul healthcare.

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