Another Gain of Function Scandal?

AP Photo/J. Scott Applewhite

Yesterday I wrote about a Fauci-led coverup of experiments on beagles. 

Today, I guess, is another Fauci's coverup day. Of course, every day is really Fauci coverup day, but in this case, I have another specific and verifiable case to discuss. 

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The virus this time is Monkeypox, or as they now call it, to quit offending the perpetually offended, mPox. 

At the height of the short-lived and overblown mPox "emergency" Science Magazine published a story on the disease, its likelihood of mutating to become more transmissible (it isn't very transmissible in humans), and about the attention being paid to the virus. 

In the middle of the story, a nugget was dropped: a scientist who was quoted about the virus casually mentioned he was doing gain-of-function research on the disease, looking to make it more easily transmitted by humans. 

You may be surprised to learn that not everybody was pleased to read that, and Congress opened an investigation into what was going on. COVID, after all, was still plaguing us, and mPox popped up out of nowhere. In both cases, gain-of-function research was tied to the viruses. 

Odd, that. 

Science can’t do more than hint at how the virus might evolve as it continues to circulate. One reason is that research interest in poxviruses has dwindled after the worldwide smallpox eradication campaign ended in triumph in 1980. “I always had to start my talks by almost apologizing for working on poxviruses,” Alcamí says.

Evolutionary virologists have instead concentrated on the influenza virus, HIV, and other small viruses whose genomes consist of RNA. Poxviruses, by contrast, are made of DNA, and are much larger and more complex. With roughly 200,000 nucleotides and 200 genes, the monkeypox genome is more than 20 times the size of HIV’s. It’s not clear what many of those genes do, Moss says, let alone how they interact with each other or how changes in any of them might affect their impact on humans.

Moss has been trying for years to figure out the crucial difference between two variants of monkeypox virus: clade 2, which until recently was found only in West Africa and is now causing the global outbreak, and clade 1, believed to be much deadlier, which has caused outbreaks in the Democratic Republic of Congo for many decades. He’s found that clade 1 virus can kill a mouse at levels 1000 times lower than those needed with clade 2. To find out why, Moss and his colleagues swapped dozens of clade 2 genes, one at a time, into clade 1 virus, hoping to see it become less deadly, but with no luck so far. Now, they are planning to try the opposite, endowing clade 2 virus with genes from its deadlier relative.

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If you read that paragraph, you can see that the gain-of-function research was ongoing--messing around with the complicated genes of a slow-to-evolve virus (its genome is so large that it evolves slowly, unlike more virulent viruses) to understand it better. 

It turns out that the research had been going on for years, but the NIH and Fauci didn't want anyone to know that, so they have been stonewalling Congress

For nearly nine years Anthony Fauci’s institute concealed plans to engineer a pandemic capable mpox virus with a case fatality rate of up to 15 percent, congressional investigators revealed in a new report Tuesday.

In June 2015, a scientist at the National Institute of Allergy and Infectious Diseases received formal approval from the National Institutes of Health’s Institutional Review Board for experiments expected to engineer an mpox virus with high transmissibility and moderate mortality.

NIAID — the institute Fauci oversaw for nearly four decades and which underwrites most federally funded gain-of-function research — concealed the project’s approval from investigators with the House Committee on Energy and Commerce over the course of a 17 month-long investigation.

A new interim report describes the obstruction and secrecy around the mpox proposal as a case study in how the institute “oversees and accounts for the monitoring of potentially dangerous gain-of-function research of concern.”

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You can see why Fauci and company didn't want this to come out. First we find out that NIAID funded coronavirus gain-of-function research in Wuhan, and shockingly a coronavirus outbreak in Wuhan led to mass deaths around the world. Then, in 2022, mPox started floating around...and guess what? NIAID was messing around with that virus too!

Mpox, formerly known as monkeypox, caused a public health emergency in the U.S. from August 2022 to February 2023. It is endemic in Africa. The more deadly clade circulates in Central Africa (clade I) while the more transmissible clade circulates in West Africa (clade II). Mpox has infected more than 20,000 people and caused more than 1,000 deaths in the Democratic Republic of Congo, where clade I predominates, according to the Centers for Disease Control and Prevention — though some experts believe that is an undercount of true cases. A strain of the clade II virus drove the American outbreak.

The mpox experiment first came to light in a September 2022 article in Science.

The gain-of-function project proposed by NIAID virologist Bernard Moss would splice genes conferring high pathogenicity from the clade I virus into the more transmissible clade II virus. The new “chimeric” (combined) virus could have retained up to a 15 percent fatality rate and a 2.4 reproductive number, a measure of transmissibility indicating every sick person could infect up to 2.4 people on average, giving it pandemic potential.

 The committee’s attempts to learn more about the experiment were met with stonewalling.

NIAID maintains the experiment was never conducted, but has never provided any contemporaneous documents to support that claim such as emails or lab notebooks, according to the committee’s report.

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Of course, Fauci and NIAID to this day maintain that they didn't fund gain-of-function research on the coronavirus either, so perhaps their definitions of "fund," "gain-of-function," or what the meaning of "is" is are different than most of us. 

Just sayin'. 

HHS and NIH misled congressional investigators for nearly a year and a half, falsely denying that Moss had obtained formal approval for this gain-of-function experiment. 

The committee launched its investigation in October 2022 but was only permitted to view key documents in camera in March 2024, which confirmed NIH’s formal approval of the experiment.

The committee lays blame with officials at NIAID, who fund most federally underwritten gain-of-function research, have the subject matter expertise, and may have misled their bosses at HHS and NIH. 

For months NIAID and Moss had reported to the committee that the mpox experiment had not moved forward and that Moss had simply been spitballing with the Science reporter in 2022 without serious intention. 

However amid the committee’s investigation in May 2023 an approval from the Federal Select Agent Program for a chimera involving both clade I and clade II of the mpox virus was revoked.

Sure, NIAID approved the experiment. But no no no, it sure didn't happen! Trust us! We stonewalled for over a year because we didn't want Congress to get confused by facts or anything. 

Not to put too fine a point on it, but have you noticed that anybody who the Democrats like can stonewall Congress, ignore subpoenas, and even hold press conferences to announce their contempt for Congress and nothing happens? A Republican does that and winds up in jail. 

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Funny that. 

It is long past time that we clean house, put some of these malefactors in jail, and ban gain-of-function research funding through federal law, not temporary restrictions by the president. Just ban it. 

Is there a connection between the mPox outbreak and the NIAID research? I haven't a clue. But what I do know is that NIAID and Fauci didn't want anyone asking that question. 

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