The big picture: As the nation’s addiction crisis has unfolded, the No. 1 cause of overdose deaths has shifted from prescription drugs to heroin to fentanyl. And now cocaine — a stimulant, making it the odd man out — is also seeing a spike.

Many overdose deaths involve more than one drug, and fentanyl crops up in a lot of those cases.

What they’re saying: “Fentanyl overdose deaths, of course, keep going up. Cocaine overdose deaths [are] going up. The question we really have to get to the bottom of is: Is much of that [from] the lacing of cocaine with fentanyl? We certainly have seen some of that,” HHS Secretary Alex Azar said at an Axios event yesterday.